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Men are far more interested in casual sex than women
Men are far more interested in casual sex than women. While men need to be exceptionally attractive to tempt women to consider casual sex, men are far less choosy. The research shows that men are more likely than women to report having had casual sex and they express a greater desire for it than do women. It is also thought that women but not men raise their standards of attractiveness for a casual sex partner.
Maternal Health & Viagra
The study revealed Viagra increased the blood supply to the fetus in female sheep, supplying amino acids -- a major fuel for fetal growth. Approximately 60 ewes were mated to rams at the Texas A&M University Sheep Center. Pregnant females were randomly selected and treated with or without sildenafil citrate.
Premature ejaculation is the main men's health complaint
Premature ejaculation is the main men's health complaint. The trigger of premature ejaculation isn't clear and also the disease is believed to be mainly a psychological problem. To understand how premature ejaculation could be successfully treated, we need to present some facts related to ejaculation and its mechanism.
Treat your erectile dysfunction
Sexual arousal in men is a very complex process that involves the brain, hormones, emotions, nerves, muscles and blood vessels. Erectile dysfunction can surface when there is a problem in one or several of these areas of the body.
Acupuncture & Infertility
The origins of acupuncture can be traced back thousands of years to ancient China and Egypt. It has been used for thousands of years in Asia as a means of helping the body to work more efficiently. It has been used in China for centuries to treat infertility.
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VIAGRA (Sildenafil) is indicated for the treatment of erectile dysfunction.
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Topical treatment of erectile dysfunction
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Online pharmacy provides you, the customer, with best service and value.
An innovative drug-delivery system – nanoparticles encapsulating nitric oxide or prescription drugs – shows promise for topical treatment of erectile dysfunction (ED), according to a new study by scientists at Albert Einstein College of Medicine of Yeshiva University. The new system, tested successfully on a small number of animals, could potentially prevent side effects associated with oral erectile dysfunction medications, if study results can be replicated in humans. That could mean safer and more effective ED therapy for millions of men with heart disease and other health problems affecting erectile function. The study is published today in the online edition of the Journal of Sexual Medicine.
Tens of millions of men worldwide have benefited from oral erectile dysfunction medications such as sildenafil (Viagra), vardenafil (Levitra), and tadalafil (Cialis). However, these medications - which belong to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors - have limitations. They can cause systemic side effects that can be serious. These side effects include headache, facial flushing, nasal congestion, upset stomach, abnormal vision as well as isolated reports of hearing and vision loss. Men who've recently suffered a heart attack or stroke or have severe heart disease should use these drugs with caution or not at all. In addition, "an estimated 30 to 50 % of men with ED do not respond to oral use of PDE5 inhibitors," says senior author Kelvin P. Davies, Ph.D., associate professor of urology at Einstein.
The drug-delivery system, developed by Einstein scientists, consists of nanoparticles – each smaller than a grain of pollen – that can carry tiny payloads of various drugs or other medically useful substances and release them in a controlled and sustained manner.
The limited number of topical formulations of ED drugs has so far proven ineffective. This study was done to evaluate whether the Einstein nanoparticles, which have been shown to penetrate the skin, might allow the targeted delivery of compounds that treat ED and thereby avoid the drugs' systemic effects.
An effective topical therapy could be especially significant for those ED patients – particularly men with diabetes – who have reduced levels of nitric oxide (NO), the signaling molecule that dilates blood vessels responsible for erectile activity. These men, who often aren't helped by oral PDE5 inhibitor drugs, may benefit from direct application of NO or the PDE5 inhibitors.
The nanoparticles were tested on a total of 18 rats bred to have age-related ED. The rats were divided into three treatment groups. One group of seven rats received nanoparticles encapsulating NO. A second group of five rats received nanoparticles encapsulating NO plus an experimental ED drug called sialorphin (which has a mechanism of action different from PDE5 inhibitors). A third group of 6 received nanoparticles encapsulating NO plus tadalafil (Cialis).
Five of the seven rats treated with the NO-containing nanoparticles, and all 11 rats treated with nanoparticles encapsulating NO plus sialorphin or tadalafil showed significantly improved erectile function. None of the seven rats in a control group, which received empty nanoparticles, showed any improvement.
"Most of the animals, nearly 90 %, showed a response to treatment with the nanoparticles," says co-author Joel M. Friedman, M.D., Ph.D., professor of physiology & biophysics and of medicine. Dr. Friedman developed the nanoparticles with his son Adam Friedman, M.D., chief resident in the division of dermatology of the department of medicine at Montefiore Medical Center, The University Hospital and Academic Medical Center for Einstein.
"The response time to the nanoparticles was very short, just a few minutes, which is basically what people want in an ED medication," adds Dr. Davies. "In both rats and humans, it can take 30 minutes to one hour for oral ED medications to take effect."
Postmortem examination of the tissues at the site of administration showed no signs of local inflammation or toxicity. "In addition, when we applied the nanoparticles at therapeutic doses, we found no indication of systemic side effects," says Dr. Friedman.
The Einstein research team will carry out safety and dosing studies in rats in the coming months. Clinical studies on humans could begin in a few years if animal studies continue to show that the nanoparticle delivery system is safe and effective. But the investigators caution that the time from a proof-of-concept trial in animals to approved use in humans may be a decade or more.
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